|Description||Recombinant protein from the extracellular domain region (Asp37-Glu651) of Homo sapiens phospholipase A2 receptor 1, 180kDa (PLA2R1), transcript variant 2 (NM_001007267), with DYKDDDDK and His tag.|
|RefSeq Link||NM_001007267; NP_001007268; UniProt#: Q13018; GeneID: 22925;|
|Synonyms||CLEC13C; PLA2-R; PLA2G1R; PLA2IR; PLA2R|
|Molecular Weight||73.1 kDa|
|Purity||>90% by SDS-PAGE gel and Coomassie Blue staining|
|Applications||Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!|
|Formulation||Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives|
|Endotoxin||>Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg)|
|Background||This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]|
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