Human GCGR Protein

Description

Recombinant protein from the region (Gln27 – Asn432) of Homo sapiens glucagon receptor gene, (NM_000160), with L49C, C171A, and C401A point mutations, and a polyhistidine tag.

Host

Human cells

Tags

DYKDDDDK/His

RefSeq Link

NM_000160; NP_000151; UniProt#: P47871; GeneID: 2642;

Synonyms

GGR; GL-R

Molecular Weight

49.7 kDa

Purity

>90% by SDS-PAGE gel and Coomassie Blue staining

Applications

Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!

Formulation

Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives

Endotoxin

Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)

Background

The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010]