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Human TSHR Protein

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Name
Human TSHR Protein
Size
50 ug
Price
$398.00
Qty

Human TSHR Protein

Description
Recombinant protein from the extracellular domain (Met22-Ser280) of homo sapiens thyroid stimulating hormone receptor (TSHR), transcript variant 1 (NM_000369), with a human IgG1 Fc tag.
Host
Human cells
Source
ECY213571
RefSeq Link
NM_000369; NP_000360; UniProt#: P16473; GeneID: 7253;
Synonyms
CHNG1; hTSHR-I; LGR3
Molecular Weight
56 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].

SDS-Page Image
Fig 1 : SDS-Page Image
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