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Human KDR / VEGFR2 Protein

SKU
Name
Human KDR / VEGFR2 Protein
Size
50 ug
Price
$398.00
Qty

Human KDR / VEGFR2 Protein

Description
Recombinant protein from the second and third Ig-like C2-type domains (D120-T320) of homo sapiens kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR) (NM_002253), with a polyhistidine tag.
Host
Human cells
Tags
His
Source
ECY211672
RefSeq Link
NM_002253; NP_002244; UniProt#: P35968; GeneID: 3791;
Synonyms
CD309; FLK1; VEGFR; VEGFR2
Molecular Weight
25.1 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

SDS-Page Image
Fig 1 : SDS-Page Image
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