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Human PD-1 Protein

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Human PD-1 Protein
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Price
$398.00
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Human PD-1 Protein

Description
Recombinant protein from the extracellualr domain (Leu25-Gln167) of homo sapiens programmed cell death 1 (PDCD1) (NM_005018), with a DYKDDDDK snd polyhistidine tag.
Host
Human cells
Source
ECY205091
RefSeq Link
NM_005018; NP_005009; UniProt#: Q15116; GeneID: 5133;
Synonyms
CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2
Molecular Weight
18 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008].

SDS-Page Image
Fig 1 : SDS-Page Image
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