Human CD40LG Protein
Recombinant protein from the extracellular domain (Met113-Leu261) of homo sapiens CD40 ligand (CD40LG) (NM_000074), fused with the extracellular domain (Pro134-Leu281) of homo sapiens Fas ligand (FASLG), transcript variant 1 (NM_000639) , with an human IgG1 Fc tag.
CD154; CD40L; gp39; hCD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP
>90% by SDS-PAGE gel and Coomassie Blue staining
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]
Fig 1 : SDS-Page Image
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