Recombinant Human TMPRSS2 Protein
Recombinant protein of the extracellular domain (M109-G492) of human transmembrane protease serine 2 (TMPRSS2), with an c-terminal polyhistidine tag.
>90% by SDS-PAGE gel and Coomassie Blue staining
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
Fig 1 : SDS-Page Image
Customers who come to this page are also interested in the following products:
There's no citations at this moment.
There's no FAQs at this moment.
There's no reviews at this moment.