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Human ACSL5 protein

SKU
Name
Human ACSL5 protein
Size
50 ug
Price
$398.00
Qty

Human ACSL5 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens acyl-CoA synthetase long chain family member 5 (ACSL5), transcript variant 3 (NM_203380), with a His tag.
Host
Human cells
Tags
His
RefSeq Link
NM_203380; NP_976314; UniProt#: Q9ULC5; GeneID: 51703;
Synonyms
ACS2; ACS5; FACL5
Molecular Weight
75.8 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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