Human ARHGEF7 protein

Description

Recombinant protein from the full-length sequence of Homo sapiens Rho guanine nucleotide exchange factor 7 (ARHGEF7), transcript variant 5 (NM_001113513), with a DYKDDDDK tag.

Host

Human cells

Tags

DYKDDDDK

RefSeq Link

NM_001113513; NP_001106985; UniProt#: Q14155; GeneID: 8874;

Synonyms

BETA-PIX; COOL-1; COOL1; Nbla10314; P50; P50BP; P85; P85COOL1; P85SPR; PAK3; PIXB

Molecular Weight

73 kDa

Purity

>90% by SDS-PAGE gel and Coomassie Blue staining

Applications

Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!

Formulation

Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives

Endotoxin

Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)

Background

This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Mar 2016].