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Human KEAP1 protein

SKU
Name
Human KEAP1 protein
Size
50 ug
Price
$398.00
Qty

Human KEAP1 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens kelch like ECH associated protein 1 (KEAP1), transcript variant 2 (NM_012289), with a His tag.
Host
Human cells
Tags
His
RefSeq Link
NM_012289; NP_036421; UniProt#: Q14145; GeneID: 9817;
Synonyms
INrf2; KLHL19
Molecular Weight
69.5 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008].

SDS-Page Image
Fig 1 : SDS-Page Image
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