Human FGL1 protein

Description

Recombinant protein from the full-length sequence of Homo sapiens fibrinogen like 1 (FGL1), transcript variant 1 (NM_004467), with a His tag.

Host

Human cells

Tags

His

RefSeq Link

NM_004467; NP_004458; UniProt#: Q08830; GeneID: 2267;

Synonyms

HFREP1; HP-041; LFIRE-1; LFIRE1

Molecular Weight

34 kDa

Purity

>90% by SDS-PAGE gel and Coomassie Blue staining

Applications

Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!

Formulation

Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives

Endotoxin

Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)

Background

Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008].