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Human NFKB2 protein

SKU
Name
Human NFKB2 protein
Size
50 ug
Price
$398.00
Qty

Human NFKB2 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens nuclear factor kappa B subunit 2 (NFKB2), transcript variant 1 (NM_001077494), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_001077494; NP_001070962; UniProt#: Q00653; GeneID: 4791;
Synonyms
CVID10; H2TF1; LYT-10; LYT10; NF-kB2; p100; p52
Molecular Weight
96.7 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013].

SDS-Page Image
Fig 1 : SDS-Page Image
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