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Human THRA protein

SKU
Name
Human THRA protein
Size
50 ug
Price
$398.00
Qty

Human THRA protein

Description
Recombinant protein from the full-length sequence of Homo sapiens thyroid hormone receptor alpha (THRA), transcript variant 2 (NM_003250), with a His tag.
Host
Human cells
Tags
His
RefSeq Link
NM_003250; NP_003241; UniProt#: P10827; GeneID: 7067;
Synonyms
AR7; c-ERBA-1; CHNG6; EAR7; ERB-T-1; ERBA; ERBA1; NR1A1; THRA1; THRA2
Molecular Weight
54.6 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

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