Recombinant Human Neuopilin-1/NRP1 Protein
Recombinant Human Neuopilin-1/NRP1 Protein
Description
Recombinant protein of the soluble form (Phe22-Lys644) from homo sapiens neuropilin 1 (NRP1), transcript variant 2 (NM_001024628), with a polyhistidine tag.
Host
Human cells
Tags
His
RefSeq Link
Synonyms
BDCA4; CD304; NP1; NRP; VEGF165R
Molecular Weight
76 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity. [UniProtKB/Swiss-Prot Function]
Fig 1 : SDS-Page Image
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