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Recombinant Human IL13 protein

SKU
Name
Recombinant Human IL13 protein
Size
50 ug
Price
$398.00
Qty

Recombinant Human IL13 protein

Description
Recombinant protein of Homo sapiens interleukin 13 (IL13), transcript variant 1 (NM_002188.3), with a His tag.
Host
Human cells
Tags
His
RefSeq Link
NM_002188; NP_002179; UniProt#: P35225; GeneID: 3596;
Synonyms
IL-13; P600
Molecular Weight
16 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008].

SDS-Page Image
Fig 1 : SDS-Page Image
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