Recombinant Human THBD Protein
Recombinant protein of the extracellular domain (A19-S515) of human thrombomodulin (THBD), NM_000361.3, with a polyhistidine tag.
AHUS6; BDCA3; CD141; THPH12; THRM; TM
>90% by SDS-PAGE gel and Coomassie Blue staining
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. [UniProtKB/Swiss-Prot Function]
Fig 1 : SDS-Page Image
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