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Human IL6 Protein

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Name
Human IL6 Protein
Size
50 ug
Price
$398.00
Qty

Human IL6 Protein

Description
Recombinant protein from the secreted form of homo sapiens interleukin 6 (IL6), transcript variant 1 (NM_000600), with a polyhistidine and DYKDDDDK tag.
Host
Human cells
Source
ABA23964
RefSeq Link
NM_000600; NP_000591; UniProt#: P05231; GeneID: 3569;
Synonyms
BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6
Molecular Weight
23 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015].

SDS-Page Image
Fig 1 : SDS-Page Image
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