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Human PDE5A protein

SKU
Name
Human PDE5A protein
Size
50 ug
Price
$398.00
Qty

Human PDE5A protein

Description
Recombinant protein from the full-length sequence of Homo sapiens phosphodiesterase 5A (PDE5A), transcript variant 2 (NM_033430), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_033430; NP_236914; UniProt#: O76074; GeneID: 8654;
Synonyms
CGB-PDE; CN5A; PDE5
Molecular Weight
94.6 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5&apos;-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

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