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Human TXNIP protein

SKU
Name
Human TXNIP protein
Size
50 ug
Price
$398.00
Qty

Human TXNIP protein

Description
Recombinant protein from the full-length sequence of homo sapiens thioredoxin interacting protein (TXNIP), transcript variant 1 (NM_006472), with a His tag.
Host
Human cells
Tags
His
RefSeq Link
NM_006472; NP_006463; UniProt#: Q9H3M7; GeneID: 10628;
Synonyms
ARRDC6; EST01027; HHCPA78; THIF; VDUP1
Molecular Weight
43.5 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015].

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