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Human RSPO1 protein

SKU
Name
Human RSPO1 protein
Size
50 ug
Price
$398.00
Qty

Human RSPO1 protein

Description
Recombinant protein from the full-length sequence of homo sapiens R-spondin 1 (RSPO1), transcript variant 1 (NM_001038633), with a His tag.
Host
Human cells
Tags
His
RefSeq Link
NM_001038633; NP_001033722; UniProt#: Q2MKA7; GeneID: 284654;
Synonyms
CRISTIN3; RSPO
Molecular Weight
28.8 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014].

SDS-Page Image
Fig 1 : SDS-Page Image
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