Human TMX2 protein
Human TMX2 protein
Description
Recombinant protein from the full-length sequence of Homo sapiens thioredoxin related transmembrane protein 2 (TMX2), transcript variant 1 (NM_015959), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
Synonyms
CGI-31; PDIA12; PIG26; TXNDC14
Molecular Weight
21.9kD
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines. [provided by RefSeq, Jan 2017]
Fig 1 : SDS-Page Image
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