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Human SPPL2B protein

SKU
Name
Human SPPL2B protein
Size
50 ug
Price
$398.00
Qty

Human SPPL2B protein

Description
Recombinant protein from the full-length sequence of homo sapiens signal peptide peptidase like 2B (SPPL2B), transcript variant 3 (NM_001077238), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_001077238; NP_001070706; UniProt#: Q8TCT7; GeneID: 56928;
Synonyms
IMP-4; IMP4; PSH4; PSL1
Molecular Weight
56.3 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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