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Human PHLPP1 protein

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Name
Human PHLPP1 protein
Size
50 ug
Price
$398.00
Qty

Human PHLPP1 protein

Description
Recombinant protein from the full-length sequence of homo sapiens PH domain and leucine rich repeat protein phosphatase 1 (PHLPP1) (NM_194449), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_194449; NP_919431; UniProt#: O60346; GeneID: 23239;
Synonyms
PHLPP; PLEKHE1; PPM3A; SCOP
Molecular Weight
184.5 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011].

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