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Human PTPRR protein

SKU
Name
Human PTPRR protein
Size
50 ug
 

Human PTPRR protein

Description
Recombinant protein from the full-length sequence of Homo sapiens protein tyrosine phosphatase receptor type R (PTPRR), transcript variant 2 (NM_130846), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_130846; NP_570897; UniProt#: Q15256; GeneID: 5801;
Synonyms
EC-PTP; PCPTP1; PTP-SL; PTPBR7; PTPRQ
Molecular Weight
46.4 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011].

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