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Human LIPA protein

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Human LIPA protein
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Price
$398.00
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Human LIPA protein

Description
Recombinant protein from the full-length sequence of homo sapiens lipase A, lysosomal acid, cholesterol esterase (LIPA), transcript variant 1 (NM_001127605), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_001127605; NP_001121077; UniProt#: P38571; GeneID: 3988;
Synonyms
CESD; LAL
Molecular Weight
43 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation. [UniProtKB/Swiss-Prot Function]

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