Human UCHL1 protein

Description

Recombinant human UCHL1 protein expressed from target gene encoding the sequence of full-length protein with a polyhistidine tag at the C-terminus.

Host

Human 293 cells

Source

Expressed and purified from in vitro cell culture of Human 293 cells

RefSeq Link

NM_004181; NP_004172; UniProt#: P09936; GeneID: 7345;

Synonyms

HEL-117; NDGOA; PARK5; PGP 9.5; PGP9.5; PGP95; Uch-L1

Molecular Weight

27.9 kDa

Purity

>90% by SDS-PAGE gel and Coomassie Blue staining

Applications

Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!

Formulation

Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives

Endotoxin

Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)

Background

The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009]