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Human IGFBP3 protein

SKU
Name
Human IGFBP3 protein
Size
50 ug
Price
$398.00
Qty

Human IGFBP3 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens insulin like growth factor binding protein 3 (IGFBP3), transcript variant 2 (NM_000598), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_000598; NP_000589; UniProt#: P17936; GeneID: 3486;
Synonyms
BP-53; IBP3
Molecular Weight
31.7 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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