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Human MGMT protein

SKU
Name
Human MGMT protein
Size
50 ug
Price
$398.00
Qty

Human MGMT protein

Description
Recombinant protein from the full-length sequence of homo sapiens O-6-methylguanine-DNA methyltransferase (MGMT) (NM_002412), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_002412; NP_002403; UniProt#: B4DEE8; GeneID: 4255;
Synonyms
O6-methylguanine-DNA methyltransferase; OTTHUMP00000020741; methylguanine-DNA methyltransferase; O-6-methylguanine-DNA methyltransferase
Molecular Weight
23.8kD
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. [UniProtKB/Swiss-Prot Function]

SDS-Page Image
Fig 1 : SDS-Page Image
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