Human HTRA1 protein
Description
Recombinant protein from the full-length sequence of homo sapiens HtrA serine peptidase 1 (HTRA1) (NM_002775), with a DYKDDDDK tag.
Synonyms
ARMD7; CADASIL2; CARASIL; HtrA; L56; ORF480; PRSS11
Molecular Weight
51.3 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein
(<1EU /µg)
Background
This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008].
Fig 1 : SDS-Page Image
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