|Description||Recombinant protein from the full-length sequence of homo sapiens HtrA serine peptidase 1 (HTRA1) (NM_002775), with a His tag.|
|RefSeq Link||NM_002775; NP_002766; UniProt#: Q92743; GeneID: 5654;|
|Synonyms||ARMD7; CADASIL2; CARASIL; HtrA; L56; ORF480; PRSS11|
|Molecular Weight||49 kDa|
|Purity||>90% by SDS-PAGE gel and Coomassie Blue staining|
|Applications||Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!|
|Formulation||Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives|
|Endotoxin||>Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg)|
|Background||This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008].|
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