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Human TK2 protein

SKU
Name
Human TK2 protein
Size
50 ug
Price
$398.00
Qty

Human TK2 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens thymidine kinase 2 (TK2), transcript variant 1 (NM_004614), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_004614; NP_004605; UniProt#: O00142; GeneID: 7084;
Synonyms
MTDPS2; MTTK; SCA31
Molecular Weight
31 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine. The encoded enzyme localizes to the mitochondria and is required for mitochondrial DNA synthesis. Mutations in this gene are associated with a myopathic form of mitochondrial DNA depletion syndrome. Alternate splicing results in multiple transcript variants encoding distinct isoforms, some of which lack transit peptide, so are not localized to mitochondria. [provided by RefSeq, Dec 2012]

SDS-Page Image
Fig 1 : SDS-Page Image
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