Human MSH2 protein
Recombinant protein from the full-length sequence of Homo sapiens mutS homolog 2 (MSH2), transcript variant 1 (NM_000251), with a DYKDDDDK tag.
COCA1; FCC1; HNPCC; HNPCC1; LCFS2
>90% by SDS-PAGE gel and Coomassie Blue staining
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Fig 1 : SDS-Page Image
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