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Human SYMPK protein

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Human SYMPK protein
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Price
$398.00
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Human SYMPK protein

Description
Recombinant protein from the full-length sequence of homo sapiens symplekin (SYMPK) (NM_004819), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_004819; NP_004810; UniProt#: Q92797; GeneID: 8189;
Synonyms
SPK; SYM
Molecular Weight
141 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3&apos;-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. [provided by RefSeq, Jul 2008]

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