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Human CD163 protein

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Human CD163 protein
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Price
$398.00
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Human CD163 protein

Description
Recombinant protein from the full-length sequence of homo sapiens CD163 molecule (CD163), transcript variant 1 (NM_004244), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_004244; NP_004235; UniProt#: Q86VB7; GeneID: 9332;
Synonyms
M130; MM130; SCARI1
Molecular Weight
125.3 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].

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