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Human IGFBP7 protein

SKU
Name
Human IGFBP7 protein
Size
50 ug
Price
$398.00
Qty

Human IGFBP7 protein

Description
Recombinant protein from the full-length sequence of homo sapiens insulin like growth factor binding protein 7 (IGFBP7), transcript variant 1 (NM_001553), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_001553; NP_001544; UniProt#: Q16270; GeneID: 3490;
Synonyms
AGM; FSTL2; IBP-7; IGFBP-7; IGFBP-7v; IGFBPRP1; MAC25; PSF; RAMSVPS; TAF
Molecular Weight
29.1 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011].

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