Human APLNR protein
Recombinant protein from the full-length sequence of homo sapiens apelin receptor (APLNR), transcript variant 1 (NM_005161), with a DYKDDDDK tag.
AGTRL1; APJ; APJR; HG11
>90% by SDS-PAGE gel and Coomassie Blue staining
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia. [UniProtKB/Swiss-Prot Function]
Fig 1 : SDS-Page Image
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