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Human APLNR protein

SKU
Name
Human APLNR protein
Size
50 ug
Price
$398.00
Qty

Human APLNR protein

Description
Recombinant protein from the full-length sequence of homo sapiens apelin receptor (APLNR), transcript variant 1 (NM_005161), with a His tag.
Host
Human cells
Tags
His
RefSeq Link
NM_005161; NP_005152; UniProt#: P35414; GeneID: 187;
Synonyms
AGTRL1; APJ; APJR; HG11
Molecular Weight
42.5 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia. [UniProtKB/Swiss-Prot Function]

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