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Human PDE6D protein

SKU
Name
Human PDE6D protein
Size
50 ug
Price
$398.00
Qty

Human PDE6D protein

Description
Recombinant protein from the full-length sequence of homo sapiens phosphodiesterase 6D (PDE6D), transcript variant 1 (NM_002601), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_002601; NP_002592; UniProt#: O43924; GeneID: 5147;
Synonyms
JBTS22; PDED
Molecular Weight
17.2 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants. [provided by RefSeq, Mar 2014]

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