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Human ELAVL1 protein

SKU
Name
Human ELAVL1 protein
Size
50 ug
Price
$398.00
Qty

Human ELAVL1 protein

Description
Recombinant protein from the full-length sequence of homo sapiens ELAV like RNA binding protein 1 (ELAVL1) (NM_001419), with a His tag.
Host
Human cells
Tags
His
RefSeq Link
NM_001419; NP_001410; UniProt#: Q15717; GeneID: 1994;
Synonyms
ELAV1; Hua; HUR; MelG
Molecular Weight
35.9 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012].

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