×
Login

Human EIF2AK2 protein

SKU
Name
Human EIF2AK2 protein
Size
50 ug
Price
$398.00
Qty

Human EIF2AK2 protein

Description
Recombinant protein from the full-length sequence of homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant 3 (NM_001135652), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_001135652; NP_001129124; UniProt#: P19525; GeneID: 5610;
Synonyms
EIF2AK1; PKR; PPP1R83; PRKR
Molecular Weight
57.2 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Contact Us
View Storefront

Related Products

Customers who come to this page are also interested in the following products:


There's no citations at this moment.


There's no FAQs at this moment.


There's no reviews at this moment.