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Human ATIC protein

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Name
Human ATIC protein
Size
50 ug
Price
$398.00
Qty

Human ATIC protein

Description
Recombinant protein from the full-length sequence of Homo sapiens 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) (NM_004044), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_004044; NP_004035; UniProt#: P31939; GeneID: 471;
Synonyms
AICAR; AICARFT; HEL-S-70p; IMPCHASE; PURH
Molecular Weight
64.4 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009].

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