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Human MEN1 protein

SKU
Name
Human MEN1 protein
Size
50 ug
Price
$398.00
Qty

Human MEN1 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens menin 1 (MEN1), transcript variant 2 (NM_130799), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_130799; NP_570711; UniProt#: O00255; GeneID: 4221;
Synonyms
MEAI; SCG2
Molecular Weight
67.3 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]

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