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Human GPT protein

SKU
Name
Human GPT protein
Size
50 ug
Price
$398.00
Qty

Human GPT protein

Description
Recombinant protein from the full-length sequence of homo sapiens glutamic--pyruvic transaminase (GPT) (NM_005309), with a His tag.
Host
Human cells
Tags
His
RefSeq Link
NM_005309; NP_005300; UniProt#: P24298; GeneID: 2875;
Synonyms
AAT1; ALT1; GPT1
Molecular Weight
54.5 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.[provided by RefSeq, Nov 2009].

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