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Human PAK1 protein

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Name
Human PAK1 protein
Size
Price
$398.00
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Human PAK1 protein

Description
Recombinant protein from the full-length sequence of homo sapiens p21 protein (Cdc42/Rac)-activated kinase 1 (PAK1), transcript variant 1 (NM_001128620), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_001128620; NP_001122092; UniProt#: Q13153; GeneID: 5058;
Synonyms
PAKalpha
Molecular Weight
33.6 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

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