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Human TRIM3 protein

SKU
Name
Human TRIM3 protein
Size
50 ug
Price
$398.00
Qty

Human TRIM3 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens tripartite motif containing 3 (TRIM3), transcript variant 1 (NM_006458), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_006458; NP_006449; UniProt#: O75382; GeneID: 10612;
Synonyms
BERP; HAC1; RNF22; RNF97
Molecular Weight
80.6 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008].

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