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Human RPTOR protein

SKU
Name
Human RPTOR protein
Size
50 ug
Price
$398.00
Qty

Human RPTOR protein

Description
Recombinant protein from the full-length sequence of homo sapiens regulatory associated protein of MTOR complex 1 (RPTOR), transcript variant 1 (NM_020761), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_020761; NP_065812; UniProt#: Q8N122; GeneID: 57521;
Synonyms
KOG1; Mip1
Molecular Weight
148.9 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

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