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Human SOX2 protein

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Human SOX2 protein
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Price
$398.00
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Human SOX2 protein

Description
Recombinant protein from the full-length sequence of homo sapiens SRY-box 2 (SOX2) (NM_003106), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_003106; NP_003097; UniProt#: P48431; GeneID: 6657;
Synonyms
ANOP3; MCOPS3
Molecular Weight
34.3 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008].

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