Human MS4A2 protein
Recombinant protein from the full-length sequence of homo sapiens membrane spanning 4-domains A2 (MS4A2), transcript variant 1 (NM_000139), with a His tag.
APY; ATOPY; FCER1B; FCERI; IGEL; IGER; IGHER; MS4A1
>90% by SDS-PAGE gel and Coomassie Blue staining
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy. [UniProtKB/Swiss-Prot Function]
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