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Human MS4A2 protein

SKU
Name
Human MS4A2 protein
Size
50 ug
Price
$398.00
Qty

Human MS4A2 protein

Description
Recombinant protein from the full-length sequence of homo sapiens membrane spanning 4-domains A2 (MS4A2), transcript variant 1 (NM_000139), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_000139; NP_000130; UniProt#: Q01362; GeneID: 2206;
Synonyms
APY; ATOPY; FCER1B; FCERI; IGEL; IGER; IGHER; MS4A1
Molecular Weight
26.4 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy. [UniProtKB/Swiss-Prot Function]

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