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Human CUL3 protein

SKU
Name
Human CUL3 protein
Size
50 ug
Price
$398.00
Qty

Human CUL3 protein

Description
Recombinant protein from the full-length sequence of homo sapiens cullin 3 (CUL3), transcript variant 1 (NM_003590), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_003590; NP_003581; UniProt#: Q13618; GeneID: 8452;
Synonyms
CUL-3; PHA2E
Molecular Weight
88.7 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].

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