Human HLA-G protein

Description

Recombinant protein from the full-length sequence of homo sapiens major histocompatibility complex, class I, G (HLA-G-G) (NM_002127), with a DYKDDDDK tag.

Host

Human cells

Tags

DYKDDDDK

RefSeq Link

NM_002127; NP_002118; UniProt#: P17693; GeneID: 3135;

Synonyms

MHC-G

Molecular Weight

35.6 kDa

Purity

>90% by SDS-PAGE gel and Coomassie Blue staining

Applications

Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!

Formulation

Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives

Endotoxin

Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)

Background

Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells. [UniProtKB/Swiss-Prot Function]