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Human DOCK8 protein

SKU
Name
Human DOCK8 protein
Size
50 ug
Price
$398.00
Qty

Human DOCK8 protein

Description
Recombinant protein from the full-length sequence of homo sapiens dedicator of cytokinesis 8 (DOCK8), transcript variant 2 (NM_001190458), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_001190458; NP_001177387; UniProt#: Q8NF50; GeneID: 81704;
Synonyms
HEL-205; MRD2; ZIR8
Molecular Weight
227.5 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010].

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