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Human GALT protein

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Human GALT protein
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$398.00
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Human GALT protein

Description
Recombinant protein from the full-length sequence of homo sapiens galactose-1-phosphate uridylyltransferase (GALT), transcript variant 1 (NM_000155), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_000155; NP_000146; UniProt#: P07902; GeneID: 2592;
Synonyms
OTTHUMP00000021298; galactose-1-phosphate uridyl transferase; galactose-1-phosphate uridylyltransferase
Molecular Weight
43.2 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

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